EBM Research Project(s)

Doctors who use evidence from clinical trials are more likely to identify the best drug or device or specialist for any unique medical condition.

Client requested evidence on the safety of Hip Replacement surgery

Out of 2,561 patients who underwent hip resurfacing, 211 of them (8%) needed revision surgery, while out of 173,364 patients who underwent total hip arthroplasty, 2,031 of them (1%) needed revision surgery
Our initial interview process with each client enables The Qure team to create a custom “framed” question(s) that matches your unique medical condition and needs. Our evidence technologies and services then will be able to find, store and deliver evidence that answers your “framed” question(s).

Evidenza has partnered with The Qure and Doctor Evidence to use its multi-million dollar software platform on behalf of consumers and physicians. It is called The Qure EBM Solution. All the current healthcare sites on the web, including WebMD, only provide opinions, recommendations and reviews. These opinion-based websites do not provide access to the evidence that determines whether or not a therapy is effective and/or safe. The Qure finds and delivers the actual evidence that physicians, hospitals, payers and policy-makers use. Now consumers can get the same evidence that the entire health care industry is using.

Client requested evidence on the most evidence therapy for Pancreatic Cancer

Out of 1,753 patients who took Erlotinib to treat their pancreatic cancer, 147 of them (8%) had disease response within 3 years, while out of 1,518 patients who took placebo, 73 (5%) of them had disease response within 3 years.

The core purpose of The Qure EBM Solution is finding and delivering relevant evidence (found in clinical trials) to both concierge medicine physicians and their patients.  For over 10 years physicians with private medicine practices have been relying on either Doctor Evidence or The Qure to find and deliver evidence that would help them identify the best therapies for their unique patient population.  Many patients who are members of concierge medicine practices expect their primary doctors and/or their specialists to rely on real evidence to make the best recommendations on their behalf.  Thus many private medicine patients/members also rely on The Qure to provide the same evidence services when they get diagnosed with a medical problem.

Concierge medicine promises high-quality service and high-quality care.  To fulfill the promise of providing the “highest quality of care,” physicians need access to the best evidence available for any medical problem.  Concierge medicine doctors who use evidence from clinical trials are more likely to identify the best drug or device or specialist for any unique medical condition.  Relying on training, experience, referral networks, review articles, seminars, standards of practice is not enough.  Physicians who merge their expertise with an analysis of the data found in clinical trials are in the best position to find the best therapy.

Client requested evidence on the most effective therapy for localized prostate cancer

Out of 42,616 people who have localized prostate cancer and chose to have their prostate removed, 642 of them (1%) died due to prostate cancer within 20 years, while out of 23,401 people who have localized prostate cancer and chose no treatment or active surveillance, 1124 of them (4%) died due to prostate cancer within 20 years.

What used to be nearly impossible for physicians to do in the past is now easy to accomplish.  Now physicians can use The Qure to answer any medical question with real evidence.

Anyone with basic internet and math skills can use our evidence databases to determine which therapy is most safe and effective for their unique medical condition. In addition we can find and deliver evidence on what causes a disease and/or the incidence rate of the disease.

The Qure works with concierge medicine doctors and their patients to make sure they are getting all the relevant evidence that will answer any framed question.  Here is short list of projects done on behalf of private medicine doctors and their patients:

  • Finding surgeons with the best survival rates for prostatectomy for localized prostate cancer.  And comparing the survival rates to watchful waiting.
  • Determining rate of cancer secondary to metal hip replacements.
  • Rate of colon cancer detection by screening colonoscopy in asymptomatic patients.
  • Stroke, MI and death rates for different statin drugs.  And compared to placebo.
  • Flu Vaccine efficacy for healthy adults
  • And hundreds more

Client requested the evidence on the most effective therapy for Vulvovaginal Atrophy

Out of 150 patients who used hormone treatment, 105 of them (70%) reported less painful sexual intercourse within 12 weeks, while out of 155 patients who used placebo, 62 of them (40%) reported less painful sexual intercourse within 12 weeks.

The entire process includes:

  • Framing question with both patient and their physician by email and/or phone
  • Finding and retrieving all the relevant studies (including relevant evidence found in unpublished resources as needed)
  • Analyzing the data and creating a custom report that is sent to patient/physician.
  • Modify project as needed based on analysis done.
  • Informed decision made by patient with their physician
  • Finding best specialists as needed that provide “best therapy” identified by the evidence (i.e.: Surgeons who perform nerve sparing prostatectomy and have their own outcome data)

Client requested evidence on the most effective therapy for Rheumatoid Arthritis

The evidence shows that out of 764 patients who used a combinations of DMARDs, 102 of them (13%) experienced a flare-up within 26 weeks, while out of 657 patients who used a combination of placebo and DMARDs, 139 of them (21%) experienced a flare-up within 26 weeks.